Features Of The Mdr1 (C3435t) Polymorphism In Non-Syndromic Congenital Orofacial Clefts
Keywords:
orofacial clefts, MDR1, C3435T polymorphism, cleft palateAbstract
The present study investigated the MDR1 (C3435T) polymorphism in patients with non-syndromic congenital orofacial clefts in Uzbekistan. Comparative analysis of allele and genotype frequencies demonstrated no statistically significant differences between affected patients and healthy controls. Based on the obtained findings, the MDR1 (C3435T) polymorphism cannot be considered an independent genetic marker associated with an increased risk of non-syndromic congenital orofacial clefts in the Uzbek population
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