Global Insights in Biomedical & Multidisciplinary Research
type: channel
description: Global Insights in Biomedical & Multidisciplinary Research (GIBMR) is a peer-reviewed, open access journal focused on advancing interdisciplinary biomedical science through laboratory innovation, biotechnology, and integrative research approaches. The journal provides a platform for researchers working at the intersection of life sciences, engineering, computational research, and medicine. By encouraging cross-disciplinary collaboration, the journal aims to support scientific discoveries that contribute to healthcare advancement and biomedical innovation. Aim Global Insights in Biomedical & Multidisciplinary Research (GIBMR) aims to promote rigorous laboratory and interdisciplinary research that integrates biomedical sciences with technological and analytical advancements. The journal seeks to encourage collaboration across scientific disciplines and provide a global platform for the dissemination of innovative research that contributes to biomedical knowledge, healthcare improvement, and scientific development. Scope The journal publishes original research articles, review articles, systematic reviews, meta-analyses, and technical reports in a broad range of interdisciplinary biomedical fields. Areas of interest include, but are not limited to: Molecular Biology and Genetics Biotechnology and Bioengineering Immunology and Microbiology Biomedical Engineering and Medical Devices Computational Biology and Bioinformatics Artificial Intelligence in Healthcare Research Experimental and Laboratory Medicine Tissue Engineering and Regenerative Sciences Nanomedicine and Biomaterials Interdisciplinary Health Sciences Research The journal particularly welcomes studies that integrate biological sciences with engineering, computational approaches, and emerging technologies to advance biomedical research and healthcare innovation. Country of Publication: Germany City: Munich Medium of publication: Online Language(s) of publication: English Frequency of publication: Monthly (12 Is…
publisher: Biomed Globe Publishing
language: en
publication name: Global Insights in Biomedical & Multidisciplinary Research
issn: 3054-5900
copyright: You are free to: Share — copy and redistribute the material in any medium or format for any purpose, even commercially. Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits. Notices: You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation. No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
items: Features Of The Somatic Pool And Dynamics Of Physical Development In Infants And Toddlers Under Various Options Of Nutritional Support
items: Biocompatibility, Corrosion Behavior, And Ion Release Characteristics Of Mg–Zn Alloys For Biodegradable Urological Stents Umida Abdujabborova
items: Benefits of Dietary Therapy in Pediatric Urate Nephropathy
items: Metagenomic monitoring in wastewater: early detection of pathogens and antibiotic resistance genes.
items: Results Of Minimally Invasive Treatment Of Complex Inguinal Hernias
items: Oxidized LDL and macrophage activation in atherosclerosis: Molecular mechanisms, immunological plasticity, and novel therapeutic strategies
items: Structure of the heart and blood vessels: Anatomical differences between arteries and veins
items: Artificial Intelligence: An Important Factor In The Development Of Modern Society
items: Comparative Analysis Of Interrelationship Markers Of The Cytokin System In The Blood In Patients With Rheumatoid Arthritis And Related IR
items: Impаct of Rheumаtic Fever on the Cаrdiovаsculаr System: Modern Аpproаches to Diаgnosis аnd Treаtment
items: Peat -Based Rust Modifier In Protection Of Metal Surfaces Of Agricultural Equipment From Rust
items: Features Of The Mdr1 (C3435t) Polymorphism In Non-Syndromic Congenital Orofacial Clefts
items: Promotion And Development of Youth Consciousness and Culture
items: The Importance Of Play Activities In Preschool Educational Institutions
items: Digital Childhood And Emotional Development In Children: Contemporary Psycho-Pedagogical Challenges
items: Diabetic Gangrene Of The Lower Limbs – Analysis Of Treatment Outcomes And Long-Term Survival
items: Menopause: Hormonal Changes and Modern Treatment Approaches
items: Methods For Developing Algorithmic Thinking
items: Influence Of Harmful And Hazardous Factors Of The Production Environment On The Health Of Workers In The Production Of Metal Structures
items: Free Radicals, Oxidative Stress And Antioxidant Systems
items: Analysis and Current Problems of Greening Small Cities in Arid Conditions
items: The Role Of Preventive Healthcare In Reducing NonCommunicable Diseases Among Urban Population
items: Digital Health Technologies And Their Impact On Public Healthcare Management
items: Genetic Aspects Of Otosclerosis: Current Data On Predisposition, Candidate Genes, And Clinical Significance
items: https://www.biomedglobe.com/index.php/gibmr/article/view/59
items: Predicting the Course of Pregnancy in Women with Diabetes Mellitus After COVID-19 Using Continuous Glucose Monitoring (CGM) Systems and Digital Remote Monitoring Devices
items: Morphological Basis Of Mammary Gland Differentiation In Rat Offspring Under Conditions Of Impaired Thyroid Functional Activity
items: The Impact Of Academic Stress On Emotional Burnout Among Medical University Students
items: Physical Health: How Our Character Traits Affect Our Body
items: Gut Microbiota Alterations In Patients With Chronic Heart Failure And Chronic Kidney Disease

Features Of The Somatic Pool And Dynamics Of Physical Development In Infants And Toddlers Under Various Options Of Nutritional Support
type: item
description: Physical development in infants and toddlers serves as an integral marker of overall health status and is substantially determined by the pattern of infant feeding during the first year of life [1, 2, 6]. This article presents the results of a prospective cohort study investigating anthropometric parameters (body weight, length/height, and body mass index) in infants and toddlers who received exclusive breastfeeding, formula feeding, or mixed feeding [3, 4, 7]. Specific patterns of growth velocity and somatotypic characteristics were identified depending on the type of nutritional support [5, 8, 9]. It is demonstrated that formula feeding is associated with accelerated rates of weight gain and an increased risk of developing overweight in subsequent periods, thereby validating the concept of early metabolic programming [10, 12]. The necessity of personalized monitoring of physical development using WHO growth standards is substantiated
subject: Articles
  topic: section
subject: infants and toddlers
  topic: keywords
subject: physical development
  topic: keywords
subject: breastfeeding
  topic: keywords
creator: Uralov Shukhrat Mukhtarovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 87
ending page: 92

Biocompatibility, Corrosion Behavior, And Ion Release Characteristics Of Mg–Zn Alloys For Biodegradable Urological Stents Umida Abdujabborova
type: item
description: The development of biodegradable metallic materials has become a major focus in modern biomedical engineering due to their ability to provide temporary mechanical support while eliminating the need for secondary surgical removal. Magnesium-based alloys have emerged as promising candidates for biodegradable implants owing to their favorable mechanical properties, biodegradability, and biological compatibility. The present study evaluates the corrosion behavior, ion release characteristics, and potential biocompatibility of Mg–Zn alloys intended for application as biodegradable urological stents. Particular attention is given to Mg–4Zn alloys under simulated physiological and acidic conditions. In vitro investigations demonstrated that the concentrations of released Mg²⁺ and Zn²⁺ ions remained within biologically acceptable ranges throughout the experimental period. Furthermore, Mg–4Zn alloys maintained structural integrity for up to 30 days even under conditions of elevated acidity, which simulates pathological urinary environments
subject: Articles
  topic: section
subject: Magnesium Alloys
  topic: keywords
subject: Biodegradable Stents
  topic: keywords
subject: Urology
  topic: keywords
creator: Umida Abdujabborova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 42
ending page: 47

Benefits of Dietary Therapy in Pediatric Urate Nephropathy
type: item
description: This article presents a scientifically grounded analysis of the effectiveness of dietary therapy in children aged 3-6 years with urate nephropathy. Using a specially designed 7-day dietary program, laboratory, clinical, and biochemical parameters were monitored to evaluate the impact of nutritional intervention on urinary system function. The results were compared with international studies and confirmed the effectiveness of dietary therapy. The article helps strengthen the scientific basis for dietary management in pediatric nephrology.
subject: Articles
  topic: section
subject: Dietary Therapy
  topic: keywords
subject: Diet
  topic: keywords
subject: Urate Nephropathy
  topic: keywords
subject: Biochemical Parameters
  topic: keywords
creator: Karimova Barnoxon Narmataliyevna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 82
ending page: 86

Metagenomic monitoring in wastewater: early detection of pathogens and antibiotic resistance genes.
type: item
description: This study focuses on the application of metagenomic monitoring in wastewater to serve as an early detection system for epidemiological threats and to assess the prevalence of antimicrobial resistance genes (ARGs). Wastewater acts as a collective biological mirror of a population; thus, high-throughput DNA/RNA sequencing (NGS) allows for the identification of pathogenic microorganisms before clinical cases peak. Through shotgun metagenomic sequencing, this research analyzes bacterial and viral pathogens alongside mobile resistance determinants (plasmids and integrons) present in wastewater infrastructure. The findings highlight the critical role of wastewater-based epidemiology (WBE) as a non-invasive, cost-effective early warning tool for public health surveillance and pandemic preparedness.
subject: Articles
  topic: section
subject: Metagenomics
  topic: keywords
subject: wastewater-based epidemiology
  topic: keywords
subject: antimicrobial resistance genes
  topic: keywords
creator: Ibodullayeva Sabina Sunnatillo qizi
creator: Boʻriboyeva Zuhra Umarbekovna
creator: Akmalova Sevinch San'atjon qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 77
ending page: 81

Results Of Minimally Invasive Treatment Of Complex Inguinal Hernias
type: item
description: Minimally invasive surgery has a wide range in modern surgery. The stages of endovisual intervention technology are based on diagnostic laparoscopy, which serves as the surgeon's savior in many difficult situations. If at the end of the 20th century all abdominal herniology was based on manual surgery, now visual or remote robotic surgery is preferred. Endovisual surgery is one of the safest methods for combined surgical pathology of the abdominal organs.
subject: Articles
  topic: section
subject: Complex inguinal hernia
  topic: keywords
subject: laparoscopic hernioplasty
  topic: keywords
creator: Khakimov M.Sh
creator: Sattarov O.T
creator: Yakubov O.E
creator: Fayziyev S.I
creator: Muzaffarov I.A
creator: Mardonov B.B
creator: Axmedov A.A
creator: Saidmurodov B.S
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 70
ending page: 76

Oxidized LDL and macrophage activation in atherosclerosis: Molecular mechanisms, immunological plasticity, and novel therapeutic strategies
type: item
description: This analytical article is devoted to studying the central link in the pathogenesis of atherosclerosis — the molecular interaction between oxidized low-density lipoproteins (oxLDL) and macrophages. Atherosclerosis is not just a buildup of cholesterol, but a complex chronic immune-inflammatory process in the arterial wall. The paper analyzes the absorption of oxldl by scavenger-receptors (CD36, PAFR, LOX-1), polarization of macrophages to phenotypes M1 (pro-inflammatory) and M2 (anti-inflammatory), and signaling pathways (TLR4/NF-kB, eEF2K) that control these processes. The analysis provides scientific evidence for recent scientific discoveries over the past 10 years, particularly the mechanisms by which macrophages survive in stressful conditions and the anti-atherosclerotic effects of natural compounds such as Puerarin.The findings of the study will help identify new molecular targets for atherosclerosis therapy
subject: Articles
  topic: section
subject: atherosclerosis
  topic: keywords
subject: oxLDL
  topic: keywords
subject: macrophage polarization
  topic: keywords
creator: Shoymardonova Dilnoza Sherali qizi
creator: Gaybullayeva Sarvinoz Makhmud qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 65
ending page: 69

Structure of the heart and blood vessels: Anatomical differences between arteries and veins
type: item
description: The cardiovascular system is one of the most important systems in the human body, delivering oxygen and nutrients to all cells of the body. This scientific article analyzes the anatomical structure, functional features, and differences between arteries and veins. The study examined the layers of the blood vessel walls, the level of elasticity, the effect of blood pressure, and the presence of valves. The results showed that arteries have thick, elastic walls that carry blood from the heart to the organs under high pressure, while veins have thinner walls and valves that help return blood to the heart. The study is important for understanding and preventing cardiovascular disease.
subject: Articles
  topic: section
subject: heart
  topic: keywords
subject: artery
  topic: keywords
subject: vein
  topic: keywords
subject: blood vessel
  topic: keywords
creator: Kurbanturdiyeva Dilrabo Bakhriddinovna
creator: Khojanazarova Saulekhon Jubatirovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-28
publication date: 2026-05-28
starting page: 152
ending page: 157

Artificial Intelligence: An Important Factor In The Development Of Modern Society
type: item
description: This article examines the role of artificial intelligence as one of the key factors in the development of modern society. The study analyzes the impact of artificial intelligence technologies on various fields, including education, economics, healthcare, industry, and information systems. The opportunities created by intelligent systems in increasing labor productivity, accelerating digital transformation, and improving the quality of life are highlighted. At the same time, the article discusses important issues related to the ethical, social, and security aspects of artificial intelligence. The research emphasizes that the effective and responsible use of artificial intelligence technologies serves as an important foundation for sustainable development and innovation in society.
subject: Articles
  topic: section
subject: Artificial Intelligence
  topic: keywords
subject: digital transformation
  topic: keywords
subject: modern society
  topic: keywords
creator: Boltaboyev Fakhriddin Murodovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 54
ending page: 58

Comparative Analysis Of Interrelationship Markers Of The Cytokin System In The Blood In Patients With Rheumatoid Arthritis And Related IR
type: item
description: Rheumatoid arthritis is a chronic autoimmune disease characterized by systemic inflammation and joint damage. In recent years, it has been found that a large proportion of patients with rheumatoid arthritis develop insulin resistance, suggesting that this condition is a combination of immune and metabolic disorders. Studies show a clear link between rheumatoid arthritis (RA) and insulin resistance (IR). Chronic inflammation in RA contributes to the development of carbohydrate metabolism disorders, making IR a common comorbid condition
subject: Articles
  topic: section
subject: Rheumatoid arthritis and related insulin resistance
  topic: keywords
subject: Interleukin1,6,10
  topic: keywords
subject: immunoglobulins
  topic: keywords
creator: Mukhamedova Nurkhon Khalimovna
creator: Niyozova Shodiya Saitmurod qizi
creator: Alimov Sobir Muxammad o`g`li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 6
ending page: 9

Impаct of Rheumаtic Fever on the Cаrdiovаsculаr System: Modern Аpproаches to Diаgnosis аnd Treаtment
type: item
description: Rheumаtic fever is аn аutoimmune inflаmmаtory diseаse thаt develops following phаryngeаl infection cаused by Group А βhemolytic Streptococcus, with cаrdiovаsculаr involvement representing its most severe complicаtion. The pаthogenesis of the diseаse is primаrily bаsed on the mechаnism of moleculаr mimicry, whereby аntibodies аnd T lymphocytes generаted аgаinst streptococcаl аntigens cross-reаct with myocаrdiаl, endocаrdiаl, аnd vаlvulаr tissues, leаding to immune-mediаted cаrdiаc dаmаge. This аrticle аnаlyzes the mechаnisms through which rheumаtic fever аffects the cаrdiovаsculаr system, the stаges of rheumаtic cаrditis, morphologicаl аnd functionаl аlterаtions of the cаrdiаc vаlves, аnd the long-term hemodynаmic consequences of the diseаse. Furthermore, the diаgnostic vаlue of clinicаl -mаnifestаtions, lаborаtory investigаtions, аnd instrumentаl exаminаtions including echocаrdiogrаphy, electrocаrdiogrаphy, inflаmmаtory biomаrkers, аnd serologicаl mаrkers confirming streptococcаl infection - is comprehensively discussed. The аrticle аlso reviews contemporаry therаpeutic strаtegies, including аntibаcteriаl therаpy, аnti-inflаmmаtory treаtment, mаnаgement of heаrt fаilure, secondаry prophylаxis, аnd evidence-bаsed аpproаches for the prevention of rheumаtic heаrt diseаse in аccordаnce with current internаtionаl recommendаtions.
subject: Articles
  topic: section
subject: Rheumаtic fever
  topic: keywords
subject: Rheumаtic heаrt diseаse
  topic: keywords
subject: Cаrdiovаsculаr system
  topic: keywords
creator: Аxtаmov Rаmziddin Аsliddin o‘g‘li
creator: Аbdurаhmonov Shoxijаhon O‘tkirjonovich
creator: Olimov Mironshoh
creator: Tog‘аydullаyevа Dildorа Dilmurodovnа
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 59
ending page: 64

Peat -Based Rust Modifier In Protection Of Metal Surfaces Of Agricultural Equipment From Rust
type: item
description: This article presents the results of a scientific study on the use of a protective coating made of a peat-based rust modifier to protect metal surfaces from corrosion under the influence of an aggressive environment . Corrosion of metal surfaces of agricultural machinery under the influence of an aggressive environment is one of the current problems. Therefore, in order to implement a new method of its prevention and protection, this research was carried out and positive results were achieved. It was observed that the metal surfaces were improved several times compared to conventional methods of protection, and recommendations on the method and results of application are given.
subject: Articles
  topic: section
subject: peat-based rust modifier
  topic: keywords
subject: peat-based rust modifieragriculture
  topic: keywords
subject: technique
  topic: keywords
creator: Khojimatov Azizbek Asomiddinnovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 50
ending page: 53

Features Of The Mdr1 (C3435t) Polymorphism In Non-Syndromic Congenital Orofacial Clefts
type: item
description: The present study investigated the MDR1 (C3435T) polymorphism in patients with non-syndromic congenital orofacial clefts in Uzbekistan. Comparative analysis of allele and genotype frequencies demonstrated no statistically significant differences between affected patients and healthy controls. Based on the obtained findings, the MDR1 (C3435T) polymorphism cannot be considered an independent genetic marker associated with an increased risk of non-syndromic congenital orofacial clefts in the Uzbek population
subject: Articles
  topic: section
subject: orofacial clefts
  topic: keywords
subject: MDR1
  topic: keywords
subject: C3435T polymorphism
  topic: keywords
subject: cleft palate
  topic: keywords
creator: Gulmuhammedov Pulat Baxtiyarovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 48
ending page: 49

Promotion And Development of Youth Consciousness and Culture
type: item
description: It was noted that the reforms being carried out in our country, the effective use of the methods of legal education are important in a responsible period of change. In the era of globalization, scientific and innovative development, it is necessary to adequately use the unique methods of raising the legal awareness and legal culture of the population, the best positive practices of advocacy
subject: Articles
  topic: section
subject: state
  topic: keywords
subject: society
  topic: keywords
subject: law
  topic: keywords
subject: legal education
  topic: keywords
creator: Abdurakhmanova Nodirahan Husnutdinovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 38
ending page: 41

The Importance Of Play Activities In Preschool Educational Institutions
type: item
description: This article analyzes the role of play activities in the development of children within preschool educational institutions and their impact on cognitive, physical, speech, and social development from a scientific perspective. In addition, the pedagogical significance of different types of play and the role of educators in organizing play activities are discussed.
subject: Articles
  topic: section
subject: play activity
  topic: keywords
subject: preschool education
  topic: keywords
subject: didactic game
  topic: keywords
creator: Egamberganova Yulduz Jasurbek qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 35
ending page: 37

Digital Childhood And Emotional Development In Children: Contemporary Psycho-Pedagogical Challenges
type: item
description: This article presents a systematic literature review examining the relationship between children's engagement with digital technologies and their emotional development, with a focus on contemporary psycho-pedagogical challenges. Publications from 2010 to 2024 indexed in PubMed, Scopus, PsycINFO, and Web of Science were analysed. The review addresses theoretical frameworks for understanding digital childhood, empirical evidence on the effects of screen time, social media use, and digital game engagement on emotional regulation, empathy, anxiety, and social competence in children and adolescents, as well as protective factors and evidence-based pedagogical responses. The analysis reveals a nuanced picture: while excessive and unstructured digital technology use is associated with elevated emotional dysregulation, social anxiety, and reduced empathy, moderate and purposefully scaffolded digital engagement can support emotional learning and social connection
subject: Articles
  topic: section
subject: Digital Childhood
  topic: keywords
subject: Emotional Development
  topic: keywords
subject: Screen Time
  topic: keywords
creator: Sharipova Sh.S.
creator: Fazilova L.G.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 27
ending page: 34

Diabetic Gangrene Of The Lower Limbs – Analysis Of Treatment Outcomes And Long-Term Survival
type: item
description: Diabetic ulcers are not only a common problem but also one of the serious and costly complications of diabetes. Significant risk factors for amputation in patients include male sex, a history of nicotine use, duration of foot ulcers, the presence of destructive changes in the foot, and excessive body weight. A history of ulcers increases the risk of developing another ulcer in diabetic patients. In 20–58% of patients, a new ulcer develops within one year after wound healing. Studies have shown that in patients with recurrent foot ulcers, the rate of amputations is ultimately 2.23 times higher than in patients with primary foot ulcers. To study long-term survival and treatment outcomes in patients with diabetic gangrene of the lower limbs (DGL) after limb amputation at various levels. The study is based on the analysis of treatment outcomes in 559 diabetic patients with complicated purulent-necrotic lesions of the foot (DGL) over the period from 2020 to 2023. During the follow-up of the control group, after 1 year, 89 patients remained under observation. Of these 89 patients, 60% retained weight-bearing function of the lower limb due to various operations performed at the level of the foot and toes
subject: Articles
  topic: section
subject: neuro-ischemic form of diabetic foot syndrome
  topic: keywords
subject: diabetic ulcer
  topic: keywords
creator: Agzam R. Bababekov
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 16
ending page: 26

Menopause: Hormonal Changes and Modern Treatment Approaches
type: item
description: The menopausal transition is a natural stage in a woman’s reproductive aging, accompanied by complex neuroendocrine changes and the development of clinical symptoms of varying severity. The relevance of this topic stems from the high prevalence of menopausal disorders, which significantly impact the quality of life, work capacity, and health status of middleaged women. The aim of this review is to analyze current data on hormonal changes occurring during the menopausal transition, as well as to evaluate the effectiveness of existing medical treatment methods. The review examines the characteristics of changes in the secretion of estrogens, folliclestimulating hormone, anti-Müllerian hormone, and inhibin B, as well as changes in the activity of the hypothalamic-pituitaryovarian axis and their role in the development of vasomotor, psychoemotional, and urogenital disorders. Modern approaches to the management of menopausal symptoms are presented, including menopausal hormone therapy, non-hormonal treatment methods, and lifestyle modifications. The analysis conducted indicates the need for a personalized approach to the management of women during the menopausal transition, taking into account clinical characteristics, risk factors, and the individual needs of patients.
subject: Articles
  topic: section
subject: menopausal transition
  topic: keywords
subject: menopause
  topic: keywords
subject: estrogen deficiency
  topic: keywords
creator: Yunusova S. SH
creator: Kamolova F. E
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-09
publication date: 2026-06-09
starting page: 10
ending page: 15

Methods For Developing Algorithmic Thinking
type: item
description: This article analyzes the theoretical foundations of the concept of algorithmic thinking, its role in the modern educational system, and effective methods for its development. Algorithmic thinking is the ability to analyze a problem step-by-step, decompose it into logical parts, and develop a solution based on a precise sequence. In today’s digital society, this skill is of critical importance not only in programming or information technology but also in economics, engineering, natural sciences, and social spheres. The article substantiates the effectiveness of methods such as problem-based learning, project-based learning, solving logic puzzles, working with flowcharts, and utilizing programming environments in shaping algorithmic thinking. Furthermore, practical recommendations are provided to foster independent and systemic reasoning in students. Research results indicate that developing algorithmic thinking at an early stage enhances educational quality and strengthens digital competencies
subject: Articles
  topic: section
subject: algorithmic thinking
  topic: keywords
subject: algorithm
  topic: keywords
subject: logical reasoning
  topic: keywords
creator: Zuparov Ilhom Baxodirovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-06-02
publication date: 2026-06-02
starting page: 1
ending page: 5

Influence Of Harmful And Hazardous Factors Of The Production Environment On The Health Of Workers In The Production Of Metal Structures
type: item
description: Metal fabrication is one of those industries with high levels of exposure to adverse production factors. During their work, workers are exposed to a range of harmful and hazardous factors, including industrial noise, dust, metal aerosols, welding fumes, unfavorable microclimate, significant physical exertion, and the stress of the work process. Long-term exposure to these factors can lead to the development of occupational and work-related diseases, decreased productivity, and a deterioration in the quality of life of workers.
subject: Articles
  topic: section
subject: Working conditions
  topic: keywords
subject: noise
  topic: keywords
subject: air dustiness
  topic: keywords
creator: Kurbanova Shakhnoza Irkinovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-30
publication date: 2026-05-30
starting page: 176
ending page: 180

Free Radicals, Oxidative Stress And Antioxidant Systems
type: item
description: Free radicals and of oxygen reactive forms ( KRSh ) and nitrogen reactive forms ( ARS ) aerobic in organisms mitochondrial breath to take , enzymatic processes , immune system protection reactions and exogenous environmental stressors of the impact natural product as permanent accordingly harvest become The outer atom or molecular in orbitals one or one how many unpaired electrons existence with characterized this substances short biological half decay to the period and extreme high chemical to activity As a result , they cell vital important macromolecules , including lipids , proteins , carbohydrates and nuclein acids with dynamic accordingly mutual to the effect enters [1.2]. Physiological normative in concentrations free radicals cell signal transduction within genes expression , veins tone management and immune protection coordinator important homeostatic regulators task However , this prooxidants too much outside many working release , endogenous antioxidant systems shortage or end with together when it is over , it leads to oxidative stress take It comes . This is cancer , dermatitis , cataracts , stroke and asthma such as to diseases take comes
subject: Articles
  topic: section
subject: dermatitis
  topic: keywords
subject: cataracts
  topic: keywords
subject: protection
  topic: keywords
creator: Hayitov Maqsud Samadovich
creator: Jurayev Muhammadnazar Bakhodir ogli
creator: Alimov Sabir Muhammad ogli
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-29
publication date: 2026-05-29
starting page: 158
ending page: 175

Analysis and Current Problems of Greening Small Cities in Arid Conditions
type: item
description: The article examines current problems of greening small cities located in arid climatic conditions. An analysis of green spaces in the cities of Khanabad, Yangiyo‘l, and Chinoz was carried out. The main factors contributing to the degradation of landscaping systems were identified, including high anthropogenic pressure, reduction of green areas, insufficient use of adapted tree and shrub species, violations of maintenance technologies, and lack of irrigation. Climatic, soil, and ecological characteristics of the territories affecting the sustainability of green plantings were investigated. Measures aimed at improving urban greening systems are proposed, including the reconstruction of existing plantings, expansion of plant diversity, development of vertical landscaping, and rational use of vacant urban areas.
subject: Articles
  topic: section
subject: greening
  topic: keywords
subject: small cities
  topic: keywords
subject: arid climate
  topic: keywords
subject: green spaces
  topic: keywords
creator: A.M. Yusupkhuzhayeva
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-29
publication date: 2026-05-29
starting page: 144
ending page: 151

The Role Of Preventive Healthcare In Reducing NonCommunicable Diseases Among Urban Population
type: item
description: Non-communicable diseases (NCDs) represent one of the leading public health problems worldwide and are responsible for significant mortality, disability, and economic burden. Urban populations are particularly vulnerable to chronic diseases due to sedentary lifestyles, unhealthy nutrition, environmental pollution, stress, and reduced physical activity. Preventive healthcare plays an essential role in reducing the prevalence and complications of noncommunicable diseases through early detection, health education, and lifestyle modification. The present study investigates the role of preventive healthcare in reducing non-communicable diseases among urban populations. Particular attention was devoted to health promotion strategies, preventive screening programs, vaccination coverage, public awareness campaigns, and lifestyle-related risk factors influencing population health. The obtained results demonstrated that preventive healthcare measures significantly contribute to reduction of cardiovascular diseases, diabetes, obesity, hypertension, and other chronic conditions. Early diagnosis, regular medical examinations, and community-based preventive interventions improve disease control and reduce healthcare burden
subject: Articles
  topic: section
subject: Preventive healthcare
  topic: keywords
subject: non-communicable diseases
  topic: keywords
subject: public health
  topic: keywords
creator: Kamila Uralovna Eshbayeva
creator: Gulnara Karimovna Khudaykulova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-24
publication date: 2026-05-24
starting page: 133
ending page: 143

Digital Health Technologies And Their Impact On Public Healthcare Management
type: item
description: Digital health technologies have become an essential component of modern public healthcare systems due to rapid technological progress and increasing demand for efficient healthcare management. The integration of digital solutions into healthcare practice significantly improves accessibility of medical services, accelerates information exchange, enhances patient monitoring, and supports evidence-based healthcare decision-making. The present study investigates the impact of digital health technologies on public healthcare management and evaluates their role in improving healthcare accessibility, quality of medical services, and organizational efficiency. Particular attention was devoted to electronic health records, telemedicine systems, mobile health applications, digital patient monitoring, and healthcare information technologies. The obtained results demonstrated that digital health technologies contribute to optimization of healthcare management processes, reduction of administrative workload, improvement of communication between healthcare providers and patients, and enhancement of preventive healthcare services. Telemedicine and digital monitoring systems significantly improved continuity of healthcare delivery and expanded access to medical consultation in remote areas. The study confirms that digital healthcare technologies represent an important direction in modernization of public health systems and possess substantial potential for improving healthcare efficiency, disease prevention, and long-term healthcare sustainability
subject: Articles
  topic: section
subject: digital health
  topic: keywords
subject: public healthcare management
  topic: keywords
subject: telemedicine
  topic: keywords
creator: M.M.Muyassarova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-23
publication date: 2026-05-23
starting page: 124
ending page: 132

Genetic Aspects Of Otosclerosis: Current Data On Predisposition, Candidate Genes, And Clinical Significance
type: item
description: This article presents an analytical review of current evidence on the genetic aspects of otosclerosis. Otosclerosis is considered a disorder of pathological bone remodeling of the otic capsule that most commonly causes stapes fixation and conductive or mixed hearing loss. The reviewed literature indicates that the disease is characterized by familial aggregation, autosomal-dominant inheritance with incomplete penetrance in a subset of families, and a pronounced polygenic and multifactorial background. The beststudied genetic signals involve RELN, TGFB1, BMP2, BMP4, MEPE, ACAN, SERPINF1, and FOXL1. However, several associations have not been consistently replicated across populations, highlighting substantial genetic heterogeneity. It is concluded that genetic markers cannot yet replace clinical diagnosis, but they are valuable for risk stratification in familial cases, early-onset disease, and bilateral involvement, and they provide a scientific basis for future personalized approaches
subject: Articles
  topic: section
subject: otosclerosis
  topic: keywords
subject: genetics
  topic: keywords
subject: hereditary
  topic: keywords
subject: predisposition
  topic: keywords
creator: Tairova S.F.
creator: Djurayev J.A
creator: Tairova S.F
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-22
publication date: 2026-05-22
starting page: 118
ending page: 123

https://www.biomedglobe.com/index.php/gibmr/article/view/59
type: item
title: Molecular genetic markers in predicting the clinical course of cervical cancer according to data from the Samarkand regional branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology
description: Cervical cancer (CC) remains a global health problem, particularly in developing countries. According to GLOBOCAN 2022, 604,000 new cases and 342,000 deaths from CC were recorded worldwide in 2020. In the structure of oncological morbidity and mortality in women worldwide, cervical cancer ranks fourth, and in developing countries this type of oncological pathology ranks first, while in economically developed countries it ranks third after uterine and ovarian cancer.
subject: Articles
  topic: section
subject: ranks
  topic: keywords
subject: fourth
  topic: keywords
subject: developing
  topic: keywords
creator: Oripova M.R
creator: Yorov L.Sh
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-22
publication date: 2026-05-22
starting page: 101
ending page: 117

Predicting the Course of Pregnancy in Women with Diabetes Mellitus After COVID-19 Using Continuous Glucose Monitoring (CGM) Systems and Digital Remote Monitoring Devices
type: item
description: Diabetes mellitus is a significant risk factor for complicated pregnancy. COVID-19 infection can exacerbate metabolic and vascular disorders, increasing the likelihood of adverse perinatal outcomes. In recent years, continuous glucose monitoring (CGM) systems and digital remote monitoring devices have been actively implemented to continuously monitor the physiological parameters of pregnant women
subject: Articles
  topic: section
subject: pregnancy
  topic: keywords
subject: diabetes mellitus
  topic: keywords
subject: COVID-19
  topic: keywords
creator: Umida Pulatovna Mamadalieva
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-16
publication date: 2026-05-16
starting page: 97
ending page: 100

Morphological Basis Of Mammary Gland Differentiation In Rat Offspring Under Conditions Of Impaired Thyroid Functional Activity
type: item
description: The thyroid gland plays a crucial role in regulation of metabolic, endocrine, and developmental processes within the mammalian organism. Thyroid hormones significantly influence tissue differentiation, cellular proliferation, hormonal balance, and morphofunctional maturation of reproductive organs, including mammary glands. Disturbances in thyroid functional activity during early ontogenesis may lead to structural and developmental abnormalities in hormonally dependent tissues. The present study investigates morphological features of mammary gland differentiation in rat offspring under conditions of impaired thyroid gland functional activity. Particular attention was devoted to histological organization, epithelial differentiation, stromal development, and morphometric characteristics of mammary gland structures under hypothyroid conditions. The obtained results demonstrated that thyroid dysfunction significantly affects structural maturation and differentiation processes of mammary gland tissues. Histological analysis revealed delayed epithelial development, reduced alveolar formation, stromal disorganization, vascular alterations, and decreased proliferative activity in experimental animals with impaired thyroid function
subject: Articles
  topic: section
subject: Thyroid gland
  topic: keywords
subject: hypothyroidism
  topic: keywords
subject: mammary gland differentiation
  topic: keywords
creator: Yusupjanova S. Qudratullayevna
creator: Rasulov H. A.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-27
publication date: 2026-05-27
starting page: 85
ending page: 96

The Impact Of Academic Stress On Emotional Burnout Among Medical University Students
type: item
description: Academic stress has become one of the most significant psychological problems among medical university students due to intensive educational demands, high academic workload, emotional pressure, and continuous professional responsibility. Prolonged exposure to academic stress may negatively affect students’ emotional well-being and contribute to the development of emotional burnout syndrome. The present study investigates the relationship between academic stress and emotional burnout among medical university students. Particular attention was devoted to the influence of academic overload, examination anxiety, sleep disturbances, and psychological fatigue on emotional exhaustion and academic motivation.
subject: Articles
  topic: section
subject: academic stress
  topic: keywords
subject: emotional burnout
  topic: keywords
subject: medical students
  topic: keywords
creator: Alimirzayev Nodirbek Avazbek o‘g‘li
creator: Mardonov Ulug’bek
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-16
publication date: 2026-05-16
starting page: 76
ending page: 83

Physical Health: How Our Character Traits Affect Our Body
type: item
description: This article looks at how our temperament affects our health and how it can lead to certain health problems. We are looking at this from an psychological point of view. The study looks at the ideas of I.P. Pavlov and Meyer Friedman. How they relate to heart disease, stomach problems and issues with our immune system. We found that people with a temperament are more likely to have heart problems while those with a melancholic temperament are more likely to have problems with their immune system. The goal of this article is to help us understand how our temperament can affect our health and how we can prevent health problems
subject: Articles
  topic: section
subject: Temperament
  topic: keywords
subject: health
  topic: keywords
subject: nervous system types
  topic: keywords
creator: Jurayeva Dildora Nasirdinovna
creator: Kazakov Sultonbek Kamoliddin o’g’li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-09
publication date: 2026-05-09
starting page: 73
ending page: 75

Gut Microbiota Alterations In Patients With Chronic Heart Failure And Chronic Kidney Disease
type: item
description: Chronic heart failure (CHF) and chronic kidney disease (CKD) are closely interconnected pathological conditions associated with high morbidity and mortality worldwide. Recent studies suggest that intestinal microbiota plays an important role in the progression of both cardiovascular and renal dysfunction through inflammatory, metabolic, and immune-mediated mechanisms. The aim of the present study was to investigate alterations of gut microbiota in patients with chronic heart failure and chronic kidney disease and to evaluate their association with clinical and metabolic disturbances
subject: Articles
  topic: section
subject: Gut microbiota
  topic: keywords
subject: chronic heart failure
  topic: keywords
subject: chronic kidney disease
  topic: keywords
creator: Tadjixodjayeva Yulduzxon Hayatillayevna
creator: Radjabova Gulirux Muhammadrizoyevna
creator: Shavkatxujayev Xasanxuja Nodirovich
creator: Mullayeva Sayyora Ilhomjonovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-05-09
publication date: 2026-05-09
starting page: 64
ending page: 72